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Recorded Elective: Metabolic Causes of Encephalopathy


Recorded Online Event - free to earn CME/CE credits

Release date: 1/1/2022 and Expiration date: 1/1/2023

Approved for 1.25 AMA PRA Category 1 Credits™/ 1.25 AAPA Category 1 CME credits/ 1.25 ANCC Contact Hours/1.25 CPEUs for Dieticians

Focus on diseases like urea cycle disorders, organic acidemias, hepatic porphyria

The videos below are an online replica of the classical training experience so common in teaching hospitals… shadowing a specialist as s/he sees her/his patients in clinic. Each Metabolism Elective has a theme and includes short medical overviews of selected diseases coupled with brief videos of patients/caregivers who describe their experiences in living with those diseases.

This activity is intended for neurologists and neurology trainees, nurses/nurse practitioners, physician assistants, genetic counselors, and dietitians, and other clinicians and their trainees, engaged in the care of patients who present with encephalopathy for reasons that are unclear. All electives will be recorded and posted following the live event on VMP's website.


  • Mark Korson, MD
  • Lee Stagni, patient-teacher


At the end of each training, attendees should be able to:

  1. Identify symptoms associated with “metabolic encephalopathy”
  2. Discuss the physiology underlying the neurologic manifestations associated with the featured metabolic diseases.
  3. List the testing to be done that can raise or lower suspicions about the featured metabolic diagnoses, or to confirm the diagnosis.
  4. Employ current guidelines for the diagnosis and management of patients with metabolic causes of encephalopathy.
  5. Integrate follow-up care of the patient with a geneticist familiar with metabolic disease.


  1. The topics are relevant.
  2. The presentation is pitched appropriately for the audience.
  3. The format is clinical and practical.
  4. Where possible, the patient story is included in the program (live +/- recorded presentations).
  5. Teaching is interactive and includes engaging the audience throughout with questions and case reviews.
  6. Through a combination of didactic teaching and case workshops, attendees are given the opportunity to apply the principles they have learned to (adapted) real-life cases, empowering them to better tackle such medical challenges in their clinical practice
  7. Repeated learning over time is more likely to be associated with long-term retention of the material.
  8. All essential teaching slides are provided in a handout to attendees.

Request for Continuing Education Credits:

Release date: 1/1/2022 and Expiration date: 1/1/2023

Estimated time to complete this activity one hour and 15 minutes. To receive full credit you will need to complete all three parts of the enduring material in order to receive full credit.

1. Go to
2. Login or Create a New Account (will take less than 1 minute)

  • a. If you receive a message when creating a new account that “the email you entered is already in use”, please click the Forgot my Username or Password link to have your Username and Password sent to you via email
  • b. After logging in, you may be asked to verify/update your information; after doing so, click Save at the bottom of the page

3. Type in 16994 as the 5 digit code at the top of the page, “Find Post-Test/Evaluation by Course”, and click enter.
4. Click on the activity title when it appears
5. Choose the type of credit you desire
6. Complete the online assessment
7. Receive an immediate CME/CE Certificate to download and/or print for your files

If you have questions regarding the certification of this activity, please contact PIM via email at

Joint Accreditation Statement  Jointly Accreditated Provider.jpgIn support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and Virtual Medical Practice.  Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physician Continuing Medical Education  The Postgraduate Institute for Medicine designates this enduring material activity for a maximum of 1.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Continuing Nursing Education  The maximum number of hours awarded for this Continuing Nursing Education activity is 1.25 contact hours.

AAPA Credit Designation Statement   AAPA CME.pngPostgraduate Institute for Medicine has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.25 AAPA Category 1 CME credits. Approval is valid until January 1, 2023. PAs should only claim credit commensurate with the extent of their participation.

Continuing Dietician Education  This program offers 1.25 CPEUs for dieticians.

Computer System Requirements:

Zoom account with access to DSL 15  Mbps or higher, Fiber, 4g, or 5g internet access. The higher the Mbps, the better the quality.

Disclosure of Conflicts of Interest:

Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy.  PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company. The faculty reported the following relevant financial relationships with ineligible entities related to the educational content of this CE activity:

  • Mark Korson, MD has the following to report:
    • Recordati Rare Diseases - grant recipient
    • Alnylam Pharmaceuticals, Solace Nutrition, Tessera Therapeutics - consultant
    • HemoShear Therapeutics - DMC member
    • Moderna Therapeutics - consultant (no longer active)
  • Lee Stagni, patient-teacher(s) has nothing to disclose.
  • The PIM planners and others have nothing to disclose.

Disclosure of Unlabeled Use:

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA.  The planners of this activity do not recommend the use of any agent outside of the labeled indications.  The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners.  Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development.  The information presented in this activity is not meant to serve as a guideline for patient management.  Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.


Jointly provided by Virtual Medical Practice and Postgraduate Institute for Medicine.

This activity is supported by an independent educational grant from Recordati Rare Diseases.


There is no cost for this online Metabolism Elective but we do ask you to submit the following information for the correct processing of credits.





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Part 2 of 3

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